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The School's research agenda is decidedly interdisciplinary, and is characterized by the complementarity and discourse between methodologies drawn from economics, engineering, computer science, applied mathematics, physics, archeology, cognitive and social neuroscience, art history and the analysis and management of cultural heritage. The IMT School is characterized therefore by the simultaneous presence of multiple analysis methodologies, able to interact at both the educational and the research level. We believe that surpassing the limits of any given discipline is only possible by combining solid and rigorous disciplinary competency with an aptitude for interacting with other disciplines.

The interdisciplinary nature of the School translates into the various research areas, articulated in Research Units that cover distinct disciplines, namely: archaeology and art history, including disciplines such as law, economics and the management of cultural heritage; theory and methodologies of empirical research applied to the analysis of social, financial and production systems, with particular emphasis on the analysis of the evolution of institutions, markets and socio-economic networks; cyber-physical systems that range from computer science to control techniques, computational mechanics and numerical methods for mathematical modelling and the simulation of natural and artificial physical systems and cognitive, social and computational neuroscience, focusing in particular on the in vivo study of the neurobiological correlates of cognitive functions, emotions and behaviour in economic and social spheres.